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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601ed8bb31b0d5c005b6d788ad111b251d11cc1a48760b9df888d5898dcb2e7c' 
  AND token = 'kJPWqOZeu4Ik+aVJYKl1qISTEW7rPiZQomuUkAlAM8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}