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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3914e27abd215925525c5d21a4b52d22db97f91cc1b0ba2a7cd1e02cad397b' 
  AND token = 'UqMl8cwHkhZVyD5DWnMHztAd7g3nEg13ktzF4rQg5Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}