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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46875b9b4dee60e9283f5132efabfa2e11d5531a638c4b9b1d925123a9c4a0bd' 
  AND token = 'Ws50iI7oYRwH3ZftpaRWhNjpEM5djXVEn9W87gQSi7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}