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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e92abf644142814fc87a1d1f9cfe953afefc7ce341d9a2a3339f4167663b265' 
  AND token = 'oRbcKVmRUDFjEw1CdjsrFh1tNnNWytASJK0xeW7R5Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}