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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c318d8424deaef572aca2710a11171d870a8c7248b285ca7f64f851f271f2fc' 
  AND token = 'u/jafOogMLS81HsT05rFz3dh1syNEyhfvknBCFB+Zac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}