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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a1168a58eebf58b751749848b854bc13fab4c0681963858270376b9641fa0a' 
  AND token = 'tv5kqA5osGpZ7kAVM0qkUyWgkv6hF+lwpPrrrmL9uYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}