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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e210dca6bba007328974ee6b5827c1f8a8f04c6808bbc98356a926275868ad' 
  AND token = 'cAXo2xCMSKIBlfK1RKj++C8w/Y1MaeSo9dKYMYpWqGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}