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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b2f8aa2e5bd47641739e3df1617eeac38f3bf6ad00cda42e1164a0abf75c0d9' 
  AND token = 'IusUYzlW3G+nJGJlz1dH0owdrs9bqwGSOGDcnIQz7Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}