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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8d942678f53c08d2e42c61ac5b5c2db448b220e08c4b2d3367f335bb188f7c' 
  AND token = '5uEVEJcLE/Arsb+9Xz47EgUNm1UOuQc8rd2ENgq2UdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}