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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9fa526a41a771d6720d4557cf418a7b5df1c832b9849ed8865490d1ba3de4ce' 
  AND token = '/e4tdnZzz5pUCKP9MrUDtj/kxFfeN5cm4ENgKp+ZUTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}