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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6f6f7b27d088c17a09cbe5d61789280a1a3db6a9b23f291db20836b49e73ab' 
  AND token = 'W/ZbSnIOst1P/QZWi2t/+LsCyH6aQPHkKeXfGqb4rro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}