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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ff767a3fe11f50454236a828f42782df5d362d0adbfb8200796ee0f7ff0042' 
  AND token = 'Pm3HTMjH7mrdZdxXsvwHKIWWJD6Xvs1RwPv/P7cgou0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}