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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5600b461934d136b2bf9e9ecf33399dd028d2494b2963e5f81f09cdf20d7498' 
  AND token = '2YemX5e5QrHStjUsgNofcgCCwihdds9zg1O/0eiUoDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}