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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e65dc6dec75f24426464fb4e49a1a1217909e01e38a2328c86339f879cc43e4' 
  AND token = 'Fnfyz96KOHQzKOJE0bJG1fHXYMdQCA6i8BSPtX8/yjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}