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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dee3ee5ff5ec73481ebbde370ce41dc747069fb46562eda8f996f8de888f3100' 
  AND token = '/csdrSq9EpeKLhX+Zlzf7koh4vQOpxDfU6Dhbm8aP6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}