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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4a10bda56208298bf1e8b4fa6d900b5d1bd68e0d67d0fbe64c0bb30dcad388' 
  AND token = '7MgYCYFRq3SGFTj1KfM5S3xTEkLGmXS9Qo0u3GGR1g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}