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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cebef462f8b7146a272e09396ce8bc875d21f02da55410e797fba62870763354' 
  AND token = 'SV20+KfaRLzZ5f+buYuvy8re0ctzuKUxCkCfGk2u8kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}