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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a704654f7a9567b9b93d929f2765fe1bd5dbfe407e4fcead3fe1b8ad663baf46' 
  AND token = 'CLoMg4KFRKJ3XeyWVhvV3FckuFtrTOKe70RRgDkLcVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}