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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62298339b75bc7fb33b8d6e2516de00e111bfeceba6011bbfb34051305e8223b' 
  AND token = '+8Gwj4TNq9iJ+NT31VI3GeO/i1cc5ZkF4rL/EvyC/TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}