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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d5ffe9f5970609ee58a1b053b9bba435152086f4504681a11076686c8de2ab' 
  AND token = '06w3AhSMbbiptiKAR9hcpHLNiOtONRd991VZC0b3W2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}