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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '155ce6f3821f4465337555f76c132fa372c53f3cff6bb9464cfb4fac5f752fd7' 
  AND token = 'bjLVGJMn9+vnu6oV9Ql5VXz2yMRG3GX+GOYttZZG7Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}