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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a001d4b59baa0d6c4fe305bcf69ebfb87817262222b20d138c2bb619e54120b' 
  AND token = 'Cye5t/HX4Tob6vmm1XZJJtbufWg/B5G/2ame3g4WEeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}