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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25eb71ede7704f3b5c762c04ac4141cc257181564e25613f6c32006dc19f0c2' 
  AND token = 'jxLSbtAQlp2Qd5288OK8g6RyZKNNj9/YTy0PDvr+Kjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}