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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5efe734583f099421c825ecaadcb48b955175eb9e00eac9ca2977afff74bd4' 
  AND token = '63AyESSJg2SBLr4Yo0+cI01aGN3IHKbN9DhnIVPEIFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}