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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e49d3c04146ce463045cf5dc29fe084cbbb72570f59f33ec64f6daea6b34b3' 
  AND token = 'yzMZAoplROGPii13aEq4UHEQjlEpEFJEVY2HJGL+TNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}