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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5acff1b9c845b233aa265a8b8f50581c72fc881e3fb4501fe4b6c3687ea8be6' 
  AND token = 'o+XzznUPA1O62CuCPkYDnpnuK/nKbtQYQo1m81/JMgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}