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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ce85dcbe001bdf31c6b48f1e198887b4884da9261801a264e555880c13e2f5' 
  AND token = 'bwrRyEoRfy2G6R/tIMCg/Jy1DdFpF4nRIPF9pjId+Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}