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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5df98b5e999a356e363a1799d743834a9bb1d5afa0db08c7a1b2589befac4a9' 
  AND token = 'JqrETrrQYn7NSs4PNVlvzJeas9+vTOpFZPwRTNMUidI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}