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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6631fd7d66fbff3da78c46365f5fd5815db27e3a48a1d3c4941b104c2b291b' 
  AND token = 'asREI5HbU2RzvU0icNERHPYa9tOtqXjQmqK/ptANeuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}