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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b50d62e6370af828effc2b768e26636fdcd12c75977318391548c6c546afa6' 
  AND token = 'Fe/HIiwZYn0r9K4baxwq9qALC6hxEnn+bdD+aizW/Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}