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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c42185c12cbe0909c0fee8e50a41be54af0ac7f66a5be3f7426d1b746e77359' 
  AND token = 'Se1KF07CJBaRQSBnwhwOpCd4v23znJOSWZtVkJZc6/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}