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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca9677cc82030a2e0fa9b1538ea109d3800233d765bd0c4fe20efbef1f03e0e' 
  AND token = 'IVuhQc5wFPHgd2POpnXBUmrxN7TXGA8+kiVqdHT5IGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}