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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e957189678a6c12e1bca1ac87f26de9c21d5ac0997431b8572fa48021f1cd8' 
  AND token = 'BRuZUY9Nvp7Ko8IK2UWtdT0ukNE2k1tsJumO8JQtc9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}