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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4af850a7c2fd864cf8fffaf78e53ba617ab48953560e1f963c94ba49e23855b' 
  AND token = '4bQlmt5fJC5MzSX/YkrcdrL3VWqbTMDAJ+nCSGGrCM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}