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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d7b729f9db9c750ed984459dcb1aed2d55aa627fb25194361488558e866408' 
  AND token = 'c6fT9WNVbCqVdMQ2ZBrTYXVrsnItcItAWqIZgHAu7So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}