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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5f47f5a6f49f24aab4786e9a40a7f3ae9b2ee215596246b7e45d9d519830dc' 
  AND token = 'HkYUVzY8VzJixM67/30xxfJETOdeZ2uBXpYw7+bMIS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}