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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e23b621a892acb4734368de7f24a9273f175e25f55e0b0f42e5e38b01a7b621' 
  AND token = 'arNRBgdmS/Ivi4NIYu87lLSUSn3jNU8kokGXxKNgcf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}