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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a43799e6230925951d5a45a3f16f069b5b0d1a82f66bb0d661b8e7f85587ed' 
  AND token = 'W/GtlTEnoCfRQyyUbGAJMTv/eZ45H/AGp8F8jYiT8VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}