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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47f7fdc2ff38443b90cf5f9c20c002c949eabe5af29c6a4566637124f0213976' 
  AND token = '6mCx6YlCPuzgJXDzLW1uDViveBESO3q1RtsIDllnuPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}