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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16b81f0f6d3a7db12c5e3b870615e20e174f3f024e61033d7cc2f3371c162d6' 
  AND token = 'aOZxFgTs+qt9AJEBoO9m3jn2eBC9IW1qKzoJH2539Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}