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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146095a666192d4f47902b263af0f57dd5f935997ffc90f59f290e9849985021' 
  AND token = 's9uXmQqQRyjofcjdvxvj3ldEqGH6mhR/9DTUJgbiRb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}