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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df79361e80b891a1f4c60d51dbca0eb780c4259db8d5032ca404125fd1e6ddd' 
  AND token = 'Ea2ltJX6ALRSivfr/s2XPUEBgWkLz6h8bKXf0f+rFbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}