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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e5c50097a241e0feddfa8e04fff9b69f26c3ed4a211d3f6e7cbeed4925cb8d' 
  AND token = 'ntBeDqNmvCI8+gLLS3CNCHfkqAl8uNlIIOKD5gjcIKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}