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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e1728e65470090f25dc86b014026c844c2826d44f3631443f3cc942dd56546' 
  AND token = '7A56sQsHqIxDlv62yafjJs/+ZYEGWh36NhakLflw0ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}