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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70a369819256a4a22fbb7e4063025901c211f96e61846b238f911d053a549224' 
  AND token = 'Ce3en7HAhYTR3bUtIeLZrz4Iq43umM29hlbDUh6NRb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}