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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd4f4dbc5588ad675d84a1d59130cf88b32fd5a95dc994019209ba6e7ca1cf2b' 
  AND token = 'ya6fdIc27ZmEyXwHcuj5j2iz4rUsz49faFvVv+iBbYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}