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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8827325dd1315b81c75fdac37c4d7fe9b404dc0eac0045ddffb42e35785fde76' 
  AND token = 'qxt0RqZZO2vpCz4FZFfLZ71MmF4bR+GXR92w01u4JgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}