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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82b9a1b8c4c69830701eda55306a38dadabd91c0150a41a4645b49c2c392e212' 
  AND token = 'dZWGDs2SOaB8c/mnBDr9nOFTCZOdA+FaeklhbNzeh0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}