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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c282a7ff58afb7e93697da8e3f1449a018243f23f92c8d7d2d8252c640bfa03' 
  AND token = 'nxpllZ7trB3uDH2W3zLDbJrWs4r/FW+1HKAyUS7QYJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}