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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de82f9b480557ae1be91125c96221baead72929329205944b55e14f8aeb79b4' 
  AND token = '/zXi+ylYxV4TaY9nOWHCG0MNjSDuEHdCTPA5zhKf6Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}